Meet Jimmy Lin, “Medical and Scientific Doxologist”

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March 25, 2013 Tags: Genetics, Science as Christian Calling

Today's entry was written by Jimmy Lin and Emily Ruppel. Please note the views expressed here are those of the author, not necessarily of The BioLogos Foundation. You can read more about what we believe here.

Meet Jimmy Lin, “Medical and Scientific Doxologist”

Note: A few years ago, biomedical researcher Jimmy Lin gave an interview with the Emerging Scholars Network’s (ESN) Michael Hickerson on being a scientific doxologist. Back then, Jimmy was doing four degrees concurrently, the MD/PhD at Johns Hopkins, the masters in arts religion at Reformed Theological Seminary, and a masters in health sciences at the School of Public Health. Now that he’s graduated three of the four programs (he’s still in the process of completing his MA in religion), we caught up with Jimmy on what’s he’s doing now as an updated introduction to ESN’s original interview. In this post, you’ll read both the recent conversation between Jimmy and BioLogos’ own Emily Ruppel, as well as selections from Michael Hickerson’s 2010 interview.

EMILY RUPPEL: You had a lot on your plate when you spoke with Michael Hickerson in 2012. What are you up to now?

JIMMY LIN: Currently I’m on faculty at Washington University at St. Louis, where I am a research instructor in the pathology department. Also, a year and a half ago, I founded the Rare Genomics Institute (RGI)—a nonprofit that helps find cures for people with rare diseases.

ER: What qualifies as a “rare disease”?

JL: These are diseases like cystic fibrosis and Huntingdon’s disease—diseases that affect less than 200,000 Americans each year. There are over 7000 different rare diseases, and less than 5% of them have any therapy. Altogether, they affect about 25-30 million people.

This creates what we call a “long tail problem”—it’s hard for a top-down research system to create research programs for all 7000 rare diseases. So instead, we are creating a bottom-up platform from which the patients themselves can create research projects and help fund them. We connect patients with physicians and researchers, customize a research program with top medical universities, design the experiment, and then use an online fundraising platform to fund the study through [mostly] friends and family of the patient.

Basically, we create a “foundation in a box.” By partnering with the Rare Genomics Institute, patients and their friends and families who want to study rare diseases don’t have to go through the hoops of creating their own nonprofit or lab—we do that for them. So, instead of creating 7000 different nonprofits, we create a generalized platform from which studies can be conducted.

ER: Who qualifies for care through the Rare Genomics Institute?

JL: Anyone with a rare disease can come to us. The main thing we’re doing right now is diagnosis. When families come to us, they either don’t know the disease that’s affecting them or their child, or they don’t know the gene that’s wrong.

For instance, if a child had a condition that doctors couldn’t identify, his or her parents might come to us for help. What we’d do then is sequence the genes of the mother, father, and child, and compare them to reference genome to determine what mutations each of the parents have. Depending on what the disease is and what the gene causing it is, we can filter out mutations that don’t mean anything using the parents’ genomes—then, after filtering, we can potentially pinpoint the genes that fit the genetic pattern of the disease. This is the first step.

After that, we are building infrastructure to determine the effect of these changes and a way to help. For example, after looking at the literature, we can perhaps design experiments using cells extracted from the patient; this part of the process is different for every disease. Then, if we can determine that there is, for instance, a pathway missing a specific enzyme, we can try using drugs, a bone marrow transplant, or gene therapy to try to put healthy cells into the child… But there’s a variety of diseases, of course, so there’s a variety of different approaches—and we’re just starting to explore these aspects.

ER: How did RGI get started?

JL: It really started when I was in medical school at Johns Hopkins—there was this boy that came to our clinic to be seen. My research was in cancer genome sequencing, and the family had come to our department looking for answers about what was wrong with their son. At that point, the family was almost hopeless—they had gone to so many doctors, run so many tests—I decided I wanted to try to help children like this. That’s when my friends and I decided to start the Rare Genomics Institute.

Currently, there are about 50 researchers associated with the organization, and we are all volunteers. It’s growing much, much faster and been more amazing than we’ve ever imagined—we’re already making an impact. In May of last year, we were able to discover a new disease using the world’s first crowd-sourced, crowd-funded genome. Working with researchers at Yale, we delineated a disease of which our patient was the first identified.

Right now, we’re in the middle of raising funding and hiring staff to make this organization one that is self-sustaining, and to increase its impact even more.

Excerpts from Michael Hickerson Interview

MH: …you call yourself a doxologist. What’s the full term you used in your Jubilee bio?

JL: Medical and scientific doxologist.

MH: How did you decide on that term and what does it mean to you?

JL: I listen to a bunch of teaching by J.I. Packer , who teaches theology at Regent College and is one of the leading thinkers on these things. Interestingly, before any one of his classes, he says “Theology is for doxology,” and then the whole class sings the Doxology together out loud in class. I thought, “Wow, that is so great,” because everybody sometimes learns theology just for intellectual things [instead of for worship].

That’s not just true for theology, it’s for everything: biology is for doxology; chemistry is for doxology. That’s when I started to think, I should consider myself, first and foremost, as a person who praises God in what I do. And then no longer make “Christian” the adjective, right? “Doxologist” is the noun. But then what kind of doxologist am I? So I call myself a medical and scientist doxologist. I would call someone, for example, in the marketplace, a business doxologist. Or, someone who does art, an artistic doxologist. To really have the noun as our identity, and then our vocation as just a descriptor of how we do that.

MH: That’s a great point. A noun is always stronger than the adjective. So, you want that to be the focus, rather than the add-on.

JL: In our current culture, we’re defined by our jobs. It’s having a vocation. I wanted to shift away from that. I didn’t want to be a doctor first and foremost, or a scientist, but one who praises God. And evidently, within science you don’t want to call yourself a Christian Scientist. That’s another religion, so . . .

MH: [laughs] That’s right. I run into that, as well, when I’m teaching or talking about science to Christians. You always run into that stumbling block.

JL: With “scientific doxologist,” people don’t confuse them. You do have to explain what it means. And that gets in a little story actually, on what it means about vocation. It’s a small lesson — a teaching point when you do talk to people about vocation and calling. That’s why I use it.

MH: I guess my final question would be what spiritual practices help sustain you? What helps you stay in contact with God and keep a good foundation?

JL: First, I am interested in many, many different things. I sort of mix it up in terms of spiritual practices. Besides the fundamentals, of course, of quiet time, devotional reading, and scriptural reading, I do theological study because I have to do that academically. I find a lot of time with God through the spiritual disciplines, such as times of solitude — which is very interesting for someone who is in academics to no longer think about ideas but just to be quiet before God — how silence, time to think by yourself, or sitting in silence is also something you should foster.

In terms of spiritual formation, what you really need is definitely a good community of people. I have a very supportive community at my church. I’m the deacon of devotions, so that of course keeps me on track. It encourages me as I, in my own spiritual walk, encourage other people. Fundamentally, I think for all Christians, whether you are academic or no matter your vocation or calling, being in the Word and prayer are the most important things. Doing that and being spiritually fed is what is important.

 


Jimmy Lin is a biomedical researcher. He holds an MD/PhD from Johns Hopkins University and a masters in health science from the School of Public Health and is earning an M.A. in religion at Reformed Theological Seminary.
As Web Editor, Emily Ruppel oversees the editorial content of the BioLogos website, including working with our many guest authors for our blog. She received a master’s degree in science writing from MIT and a bachelor’s degree in English from Bellarmine University. Since graduating MIT, she has worked as the Associate Director of Communications for the American Scientific Affiliation, where her favorite activity is editing and publishing God and Nature magazine, and as a freelance writer.


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Rajinder Nijjhar - #77844

March 26th 2013

Hi Brethren,

Scientists can study nature that belongs to the demiurge god of Old Testament Yahweh known as Brahma in Hindi and Khuda in Arabic but they cannot study Supernatural that belongs to our Father God, Eloheim, ParBrahm, Allah, etc. to Whom the Royal Priests represent by His grace. Christ Jesus is the anointed Royal High Priest and He performed Miracles to display the qualities of our Father. John, the Baptist worked for Yahweh and that is why Christ Jesus proclaimed that the least of the Royal Priests is greater than John, the Baptist, the Prophet Elijah. Or Supernatural is greater than the natural.

Now, Yahweh goes by works and your life is governed by your past deeds. This the Second anointed Christ = Satguru Nanak Dev Ji stressed in His Saying, “KARMI AWAE KAPRRA”. That is it is through the past Karma or works that you attain the present birth. And “NADRI MOKH DAWAAR”, it is by the grace of our Father that you find the Narrow Gate to the Vineyard of our Father where the True Vine Christ Jesus has been Planted by our Father for our Salvation. Thus, the Scientists can study the kingdom of Yahweh but not of our Supernatural Father God who works by Grace. It is by grace you come to know our Father God and this is well demonstrated in Saul to Paul. That is, it was the devotion of Saul that earned him the very Spirit of God making Him a Twin-Brother of Christ Jesus. There are many Sauls in the West seeking God but most of them seek the praises of men and they are spiritually blind addressing God and Jesus as Lords not knowing that Lords have slaves that are not allowed into the House but only the Sons of Father.

Many scientists, like Saul, have put on Dog-Collars in devotion to God but they do not know that in order to get rid of them that Jesus became the Lamb of God making us the Sons of the Most High Supernatural Father, the Royal Priests of our Royal Father.

Now, hardly any theologian know the difference between the shadow demiurge god Yahweh, Jealous and revengeful as expected of a natural man and our Real Father God, Which is loving and merciful Spirit. Oxford theologians call my views gnostic and heretic.

This subject is best studied through Seminars.

 


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